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Publications in January 2016

In January were 77 publications with chitosan topics published. In addition to China (26) and the United States (11), Egypt (6) is on the third place of nations with the most publications.

Top Journals Publications
Carbohydr Polym 14
Int J Biol Macromol 7
Mater Sci Eng C Mater Biol Appl 6
Acta Biomater 3
J Nanosci Nanotechno 2

Table: Top 5 journals with chitosan-related articles in Januray 2016
Source: GoPubMed

At GoPubMed you find further articles of January. Here we provide an interesting article for you:

Provides Chitosan a better bioavailability of antitumor drugs?

Varthya M, Pawar H, Singh C, Dora CP, Jena SK, Suresh S.

Varthya et al shown in an in vitro and in vivo study that tamoxifen loaded in a chitosan-lecithin nanoparticle improve the bioavailability of the drug in a cancer cell model as well as through the oral route. The nanoparticles with a size of around 169.66 nm shown also a prolonged in vitro release of the drug. The antitumor efficiency was significantly exhibited in the DMBA induced breast cancer model even if the tamoxifen loaded particles are administered once in three days in comparison to a daily dosage of tamoxifen alone. So chitosan containing nanoparticles shown the potential to increase the therapeutic efficiency of drugs. More details on the reported results can be found in the original article “Development of Novel Polymer-Lipid Hybrid Nanoparticles of Tamoxifen: In Vitro and In Vivo Evaluation.



chitosan, nanoparticles, bioavailability, cancer

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