Eye diseases are difficult to treat due to natural factors such as the blood-eye barrier, cornea or tear film. Polymer-based nanoparticles made of chitosan, among others, can help there to improve drug transport. In this article we would like to summarize a review on this topic.

Small interfering RNAs (siRNAs) can be used as in gene therapies for e.g. cancers such as leukemia. However, the application of these is limited by a lack of efficient drug delivery. Therefore, in the presented study, chitosan was functionalized with arginine to form nanoparticles, loaded with siRNA, and their properties as siRNA vectors were investigated.

According to HMC research (PubMed, Jan. 20, 2023), a total of 3097 publications with chitosan in the title were published in 2022. Of these, 151 were reviews with a wide variety of applications of chitosan. In this article, we would like to give you an overview of the publications and briefly introduce five of the reviews. Enjoy reading!

More than 5 million people worldwide are affected by inflammatory bowel disease. To enable good treatment, targeted and efficient drug delivery is necessary. In the presented study, a chitosan-based vancomycin loaded microgel was investigated for this purpose.