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Chitosan HCl

• also known as Chitosan hydrochloride, Chitosan chloride, Chitosani hydrochloridum
• listed in Eur. Ph., suitable for medical applications
• quality according to Eur. Ph.
• soluble in water
• Molecular formula: H-(C₈-H₁₃-N-O₅)_n-H-O(C₆H₁₁-N-O₄)_n CL-H

In 2017 we have deversified our product range for chitosan HCl. Now we provide different specifications for degree of deacetylation and viscosity /molecular weight. Also high molecular weight chitosan chloride is now available. For an overview please see the following table. Minimum order size for product 44001 is 20gram. For 54047, 54039, 54040 and 54046 the minimum order quantity is 10gram.

These are our Chitosan HCL standard products:

Chitoceuticals® Chitosan HCl	Article numbers
Parameter	44001	54040	54047	54039	54046
Degree of Deacetylation [%]	80-95	75-90	>90	75-90	>90
Viscosity [mPas]	2-200	<20	<20	20-200	20-200
Molecular weight appr. [kDa]	30-200	<300	<300	200-800	200-800
Chloride content [%]	10-20	10-20	10-20	10-20	10-20
pH	4-6	4-6	4-6	4-6	4-6
Ash content [%]	≤ 1	≤ 1	≤ 1	≤ 1	≤ 1
Protein content [%]	≤ 0.3	≤ 0.3	≤ 0.3	≤ 0.3	≤ 0.3
Microbiological tests
Total bacterial count [cfu/g]	≤ 1000	≤ 1000	≤ 1000	≤ 1000	≤ 1000
Yeast and Mould	≤ 100	≤ 1000	≤ 1000	≤ 1000	≤ 1000
Heavy Metals [ppm]
Pb	≤ 10	≤ 10	≤ 10	≤ 10	≤ 10
Hg	≤ 1	≤ 1	≤ 1	≤ 1	≤ 1

Of course we offer also GMP compliant grades with a low bioburden and endotoxin content. The following Chitoceuticals GMP compliant grades are produced in cleanrooms according to EU-GMP guidelines. Minimum order quantity 10 gram. If you need a quotation please do not hesitate to contact us. At the moment our GMP compliant grades are not yet available in the web shop.

Chitoceuticals® GMP compliant Chitosan HCl	Article numbers
Parameter	55040	55047	55039	55046
Degree of Deacetylation [%]	75-90	>90	75-90	>90
Viscosity [mPa-s]	<20	<20	20-200	20-200
Molecular weight appr. [kDa]	<300	<300	200-800	200-800
Chloride content [%]	10-20	10-20	10-20	10-20
pH	4-6	4-6	4-6	4-6
Ash content [%]	≤ 1	≤ 1	≤ 1	≤ 1
Protein content [%]	≤ 0.3	≤ 0.3	≤ 0.3	≤ 0.3
Microbiological tests
Total bacterial count [cfu/g]	≤ 100	≤ 100	≤ 100	≤ 100
Yeast and Mould	≤ 100	≤ 100	≤ 100	≤ 100
E.coli [cfu/g]	absent	absent	absent	absent
P.aeruginosa [cfu/g]	absent	absent	absent	absent
St. Aureus [cfu/g]	absent	absent	absent	absent
Salmonella [cfu/g]	absent	absent	absent	absent
Endotoxins [EU/g]	≤ 100	≤ 100	≤ 100	≤ 100
Heavy Metals [ppm]
Pb	≤ 10	≤ 10	≤ 10	≤ 10
Hg	≤ 1	≤ 1	≤ 1	≤ 1

Carboxymethylchitosan

• example of application: treatment of wounds
• soluble in water

Chitosan Lactat

• odourless
• preferred use in cosmetic applications
• soluble in water

Chitosan Acetat

• possible field of application: wound dressing used for burnings
• soluble in water

Chitosan Glutamate

• application mainly in the following pharmaceutical fields:
  • drug delivery
  • enhancement of absorption abilities of APIs
  • tissue engineering
  • enhancement of mucoadhesive properties

Buy chitosan derivatives

In our Onlineshop you can purchase small amounts of chitosan derivatives. Do you need a specific derivative? Or are you looking for a detailed offer? Don't hesitate to contact the Sales department of Heppe Medical Chitosan. You need another derivative? Address us your request - we also offer custom manufacturing.