There are numerous publications about nanoparticles with chitosan which investigate different preparation and characterization methods and possible applications. In the medical field, applications of chitosan-based nanoparticles as drug delivery system are a promising approach. You will find more information in our articles focusing on nanoparticles.
Microfluidics can precisely control the physiochemical properties of nanoparticles by mixing to the nanoliter. For this reason, nanoparticles for the transport of peptide drugs are to be developed in the study presented here with the help of chitosan from Heppe Medical Chitosan GmbH.
Cancer is difficult to treat due to its early immune invasion and metastasis. In the study presented here, the frequently used chemotherapeutic drugs 5-flourouracil and cisplatin are encapsulated in TPP cross-linked chitosan nanoparticles and their in vitro anti-cancer effect is investigated.