In 2019, many interesting and innovative research articles about chitosan and chitosan derivatives were published. In this article we present you an overview which chitosan reserach topics were important in 2019.
Publications in 2019
Here you can find summaries of interesting scientific chitin and chitosan articles published in 2019. Enjoy reading!
There are many potential applications of gold nanoparticles in medicine. Gold nanoparticles are already being used in diagnostics, as in pregnancy or HIV tests . Research on the use as a contrast agent for the localization of cancer cells and as a drug delivery system for targeted release at site of action. The surface properties of gold are optimal for functionalization, e.g. with chitosan.
Worldwide, about 2.5 million people live with the consequences of a traumatic spinal cord injury. At the injured site formation of glia scar tissue prevents the regeneration of nerve cells. To date, complete functional recovery of the spinal cord is impossible, also because the cascade of events that takes place at the injured site is not fully understood yet.
Testing for bacterial endotoxins with recombinant factor C might be included as a new general chapter in the European Pharmacopoeia. The European Pharmacopoeia has called for public consultation on the creation of a new General Chapter (2.6.32). In 2016, the Pharm. Eur. referred the rFC test as an alternative to Limulus amebocyte lysate (LAL) in Guidelines for using the test for bacterial endotoxins (Supplement 8.8 Chapter 5.1.10). The next step would be a separate chapter on testing for bacterial endotoxins using the rFC assay.
Chitosan and chitosan derivatives have different properties due to molecular parameters, such as degree of deacetylation and molecular weight. In this article, we present a paper that examined the effect of these parameters on the hemostatic effect of chitosan. Another topic is the long-term stability of chitosan hydrogels according to ICH guidelines.