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Chitosan research in 2019

In 2019, many interesting and innovative research articles about chitosan and chitosan derivatives were published. In this article we present you an overview which chitosan reserach topics were important in 2019.

In 2019, many interesting and innovative scientific articles about chitosan and chitosan derivative were published. A total of 3247 articles with the search term chitosan can be found for 2019 (Source: Pubmed, Date of access: 28.11.2019). Research in 2019 about chitosan was in relation to nanoparticles (995), hydrogels (369) and scaffolds (236). Searching for the treatment of diseases with Chitosan-based materials, the publication numbers are as following: cancer (327), cardiovascular (47), diabetes (45), osteoporosis (12).

The International Journal of Biological Macromolecules published 607 publications with the keyword chitosan, in Carbohydrate Polymers there were only half of them (284).

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 Reserach topic Title of publication Scientific journal Chitosan used
Drug delivery                       Production and Purification of Chitosan-IL-12 Bioconjugates: A Potential Platform for the Local Delivery of Biologics. Dissertation  95/500
Vancomycin-loaded chitosan aerogel particles for chronic wound applications Carbohydrate Polymers  90/1000
Acids ‘generally recognized as safe’ affect morphology and biocompatibility of electrospun chitosan/polyethylene oxide nanofibers Carbohydrate Polymers  
Biofunctionalization of TiO 2 Surfaces with Self-Assembling Layers of Oligopeptides Covalently Grafted to Chitosan ACS Biomaterials Science & Engineering  
Chitosan oral patches inspired by mussel adhesion Journal of Controlled Release  
Could spray-dried microbeads with chitosan glutamate be considered as promising vaginal microbicide carriers? The effect of process variables on the in vitro functional and physicochemical characteristics International Journal of Pharmaceutics  
Delivery of proteins encapsulated in chitosan-tripolyphosphate nanoparticles to human skin melanoma cells Colloids and Surfaces B: Biointerfaces  
Design and Characterization of Chitosan Nanoformulations for the Delivery of Antifungal Agents International Journal of Molecular Sciences  
Design of polymeric nanocapsules to improve their lympho-targeting capacity Nanomedicine  
Engineering, on-demand manufacturing, and scaling-up of polymeric nanocapsules Bioengineering & Translational Medicine  
Impact of oral astringent stimuli on surface charge and morphology of the protein-rich pellicle at the tooth–saliva interphase Colloids and Surfaces B: Biointerfaces  
Intestinal enzyme delivery: Chitosan/tripolyphosphate nanoparticles providing a targeted release behind the mucus gel barrier European Journal of Pharmaceutics and Biopharmaceutics  
Lysozyme-Responsive Spray-Dried Chitosan Particles for Early Detection of Wound Infection ACS Applied Bio Materials  
Nanocomposites of Polyoxometalates and Chitosan‐Based Polymers as Tuneable Anticancer Agents European Journal of Inorganic Chemistry  
New Gene Therapy Approach: Prelonged Virus-Like Particle Mediated RANKL Knockdown Using Chitosan Hydrogels Osteologie 2019  
Tissue regeneration      Freeze-casting porous chitosan ureteral stents for improved drainage    
Adhesion of electrosprayed chitosan coatings using silane surface chemistry Thin Solid Films  
Bioinspired calcium phosphate mineralization on Net-Shape-Nonwoven chitosan scaffolds stimulates human bone marrow stromal cell differentiation Biomedical materials  
Chitosan-based hydrogel to support the paracrine activity of mesenchymal stem cells in spinal cord injury treatment Scientific Reports  95/100
Chondrogenic differentiation and proliferation potential of human adipose-derived stem cells combined porous chitosan-based scaffolds for articular cartilage formation in vitro    
Crayfish hemocyanin on chitin bone substitute scaffolds promotes the proliferation and osteogenic differentiation of human mesenchymal stem cells Journal of Biomedical Materials Research  
Development of hydrogels based on oxidized cellulose sulfates and carboxymethyl chitosan Cellulose  
Functionalisation Multipurpose Intraperitoneal Adhesive Patches Advanced Functional Materials  
Nasal epithelial barrier dysfunction increases sensitization and mast cell degranulation in the absence of allergic inflammation Allergy  
Antibacterial effect Antibacterial effect and wound healing ability of silver nanoparticles incorporation into chitosan-based nanofibrous membranes Materials Science and Engineering: C  
The incorporation of silver to enhance the antibacterial properties of biomaterials   90/500
Oligosaccharides Assessment of Oligo-Chitosan Biocompatibility toward Human Spermatozoa ACS applied materials & interfaces  
Extraction of residual heavy metals from commercial chitosan and approach to preparation of oligochitosan hydrochloride Carbohydrate Polymers  
Chitosan composites   Effect of Different Crosslinking Strategies on Physical Properties and Biocompatibility of Freestanding Multilayer Films Made of Alginate and Chitosan Macromolecular Bioscience  
New immobilization method of anti-PepD monoclonal antibodies for the detection of Listeria monocytogenes p60 protein – Part A: Optimization of a crosslinked film support based on chitosan and cellulose nanocrystals (CNC) Reactive and Functional Polymers  
Chitosan characterisation Mechanical and Surface Properties of Resilient Denture Liners Modified with Chitosan Salts Materials Chitosan hydrochloride (CS-HCl), chitosan glutamate
Residual heavy metals in industrial chitosan: State of distribution International journal of biological macromolecules  
Characterisation of chitosan molecular weight distribution by multi-detection asymmetric flow-field flow fractionation (AF4) and SEC International Journal of Biological Macromolecules  
 Food Iron-rich chitosan-pectin colloidal microparticles laden with ora-pro-nobis (Pereskia aculeata Miller) extract Food Hydrocolloids  
Novel spider web trap approach based on chitosan/cellulose nanocrystals/glycerol membrane for the detection of Escherichia coli O157:H7 on food surfaces International Journal of Biological Macromolecules  
Mucoadhesion   Interaction Between Chitosan and Mucin: Fundamentals and Applications Biomimetics  
Vaccine Advanced nanomedicine characterization by DLS and AF4-UV-MALS Journal of Pharmaceutical and Biomedical Analysis  

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