Treffen der Controlled Release Society
Unter dem Motto „Personalisierte Medizin und Produkte für die nächste Generation“ lud die Controlled Release Society Wissenschaftler und Fachkundige aus aller Welt nach Portland, Oregon, USA ein. Chitosan ist aus vielen Laboren dieser Arbeitsgruppen nicht mehr wegzudenken.
Zum 37. Mal trafen sich die Mitglieder der Controlled Release Society, um ihre neuesten Erkenntnisse und Entwicklungen vorzustellen. In den Bereichen Impfungen, Hydrogele, Tissue Engineering, Nanopartikel, Biomaterialien, Blut-Hirn-Schranke-Technologien, Orale Absorption und siRNA-Therapie wurde mit Chitosan geforscht.
Chitosan und Chitosanderivate bilden die Forschungsgrundlage für viele Arbeitsgruppen weltweit. So zeigten Gruppen aus Korea, der Türkei, den Niederlanden, Italien, den USA, Brasilien, Saudi-Arabien, Taiwan, Portugal, Großbritannien und Deutschland, wie Chitosan im Zusammenhang mit einer kontrollierten Wirkstofffreisetzung eingesetzt werden kann.
Folgende Vorträge und Poster wurden in den oben genannten Bereichen präsentiert:
1 Impfungen |
Conjugation of ovalbumin to trimethyl chitosan improves immunogenicity of the antigen: A strategy for (mucosal) subunit vaccination: |
Slütter, B., Soema, P., Ding, Z., Verheul,R., Hennink, W., Jiskoot, W.; Leiden University, The Netherlands |
Comparison of Chitosan-based Gel and Microparticle Formulations for Mucosal Immunization Against Bovine Herpes Virus 1 (BoHV-1): |
Gunbeyaz, M., Faraji Majarashin, A., Ozkul, A., Purali, N., Senel, S.; Hacettepe University, Turkey |
N-Trimethyl Chitosan-based Formulations for Intradermal and Transcutaneous Immunization: |
Bal, S., Ding, Z., Kersten, G., Jiskoot, W., Bouwstra, J.; Leiden University, The Netherlands |
2 Hydrogele |
Photo-crosslinkable Chitosan Hydrogels as a Nerve Adhesive: |
Amoozgar, Z., Park, J., Rickett, T., Shi, R., Yeo, Y.; Purdue University, USA |
Bio-molecular Mass Transport Across Alginate Microcapsules with Genipin-Chitosan Membrane Shell:Implications for microbioreactor-based Protein Delivery: |
Ranganath, S., Tan, A., He, F., Krantz, W., Wang, C.; National University of Singapore, Singapore |
Controlled release of basic fibroblast growth factor from chitosan/heparin hydrogel: |
Yoo, H., Choi, J., Kim, H., Son, Y.; Kangwon National University, Korea |
Ionically Crosslinked Chitosan Gels for Controlled Release of Antibiotics: |
Rasul, N., Dosanjh, P., Low, W., Kenward, M., Martin, C.; University of Wolverhampton, UK |
Thermally Sensitive Gels Based on Chitosan for the Treatment of Vaginal Mucositis: |
Rossi, S., Ferrari, F., Faccendini, A., Sandri, G., Bonferoni, M., Mori, M., Puccio, A., Caramella, C.; University of Pavia, Italy |
3 Tissue Engineering |
Sustained Delivery of Acidic Fibroblast Growth Factor Carried by Chitosan/Heparin nanoparticles Following Spinal Cord Injury: |
Huang, Y., Hsu, S., Kuo, S., Cheng, H., Huang, Y.; National Taiwan Ocean University, Taiwan |
4 Nanopartikel |
Application and Preparation of Modified Water-soluble Chitosan Nanoparticles: |
Nah, J., Choi, C., Jang, M.; Sunchon National University, Korea |
Chitosan/Tripolyphosphate Nanoparticles for Zidovudine Nasal Delivery: |
Barbi, M., Carvalho,F., Kiill, C., Gremiao, M.; Unesp, Brazil |
Clobetasol-17-propionate-loaded Lecithin-Chitosan Nanoparticles: Skin Permeation and Histological Evaluation: |
Senyigit, T., Sonvico, F., Barbieri, S., Tekmen, I., Ozer, O., Santi, P., Colombo, P; Ege University, Turkey |
Chitosan-modified PLGA nanoparticles for the delivery of telomerase inhibitor 2′-O-methyl-RNA to non-small-cell lung cancer cells and tumors: |
Loretz, B., Philippi, C., Koerbel, C., Dong, M., Beisner, J., Muerdter, T., Klotz, U., Laschke, M., Menger, M., Schaefer, U., Lehr, C.;Saarland University, Germany |
Zwitterionic Chitosan as a Potential Stealth Coating Material for Cationic Nanocarriers: |
Xu, P., Yeo, Y.; Purdue University, USA |
Nanoparticles Obtained by Chitosan and Oleic or Linoleic Acid Interaction Intended for Wound Healing: Preliminary Evaluation on Fibroblasts: |
Bonferoni, M., Sandri, G. Timaç, H., Mori, M., Rossi, S., Ferrari, F., Caramella, C.; University of Pavia, Italy |
5 Biomaterialien |
Screening of M cell-homing peptide for Peyer’s patch targeting by phage display and validation of its targeting efficiency using chitosan nanoparticles: |
Cho,C., Yoo, M., Choi, J., Jiang, T., Kang, S., Choi, Y., Lee, S., Park, I., Na, H., Lee, H.; Seoul National University, Korea |
Biocompatibility of Chitosan Derivatives in Intraperitoneal Administration: |
Bajaj, G., Yeo, Y.; Purdue University, USA |
Novel tailorable thiolated trimethylated chitosans for covalently stabilized nanoparticles: |
Verheul, R., Censi, R., Van Der Wal, S., Hennink, W.;Utrecht University, The Netherlands |
6 Blut-Hirn-Schranke-Technologien |
Development of an Oligonucleotide Carrier Nanoparticulate System with Modified Chitosan Polymers: |
Kozlu, S., Capan, Y.; Hacettepe University, Turkey |
7 Orale Absorption |
Effects of Different Polymers on the Drug Release of Zolmitriptan from Sublingual Tablet Formulations: |
Bayrak, Z., Tas, C., Tasdemir, U., Erol, H., Kose Ozkan, C.,Savaser, A., Ozkan, Y.; Gülhane Military Medicine Academy, Turkey |
Formulation and in vitro studies of sodium diclofenac from hydrophilic matrix; Vueba: |
M., Chevreux, A., Pina, M.;University of Coimbra, Portugal |
A New Theophylline Chronotherapeutic Drug Delivery System for the Treatment of Nocturnal Asthma: |
Yassin, A., Al-Suwayeh, S., Aodah, A., Taha, E.; King Saud University, Saudi Arabia |
8 siRNA-Therapie |
Chemical modification of chitosan as si/shRNA gene Carrier: |
Jiang, H., Kim, Y., Arote, R., Lim, H., Cho, M., Cho, C.; Seoul National University, Korea |
Weitere Informationen zur Controlled Release Society finden Sie hier.
Quelle: Controlled Release