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GMP Chitosan, medical device chitosan, pure chitin, pharma chitosan, chitosan derivatives, GMP, Quality, producer | Heppe Medical Chitosan

Chitosan-based matrix as a carrier for bacteriophages

Due to the increasing occurrence of bacterial resistance, alternatives to antibiotics are urgently needed. The study presented here therefore aims to develop an antimicrobial chitosan film loaded with bacteriophages.

Chitosan-based wound dressings through 3D bioprinting technology

3D bioprinting can improve the treatment of wounds by producing multifunctional, personalized wound dressings. In the study presented here, hydrogel wound dressings based on galantine, sodium alginate, dopamine and quaternized chitosan with effective antioxidant, antibacterial and biocompatible properties will be fabricated via using this technology.

Chitosan-based multilayer films as wound dressings

Chronic wounds represent a major burden on the quality of life of those affected. To improve their situation, multilayer films of chitosan, alginate and the fibroblast growth factor FGF2 were prepared in the presented study and their potential as wound dressings was investigated.

CMC-containing hydrogels for the repair of skin injuries

Deeper skin injuries require appropriate wound dressings to promote healing. In the presented study, CMC-containing hyaluronic acid-dopamine hydrogels were synthesized, characterized and investigated in vivo for their wound healing properties.

Crustacean vs. mushroom - Chitin and Chitosan for wound treatment

Chitin and Chitosan offer beneficial properties for wound dressing materials, like biocompatibility, biodegradability and haemostatic effects. The biopolymer source influences the properties, processing and associated impurities of the chitin. In this article, we want to present a review, which investigated the differences between crustaceans and fungi derived chitin and chitosan regarding wound healing.

Wound treatment with chitosan

The healing process of a wound injury follows the steps of hemostasis, inflammation, cell proliferation, and regeneration until complete healing of the damaged tissue. In chronic wounds, the progress of these steps is disturbed, leaving the wounds inflamed for a long time. In an aging society with bad health habits (poor diet, little exercise), the number of chronic wounds is going to increase. Therefore, the research on materials that improve wound healing is important. The publications presented below are devoted to research about chitosan-based materials for the treatment of chronic wounds.

Optimization of wound healing with chitosan based hybrids

Optimal wound healing requires restoration of the damaged tissue by formation of new tissue and epithelialization. To support this process after injury, suitable wound dressings are required to prevent development of a chronic wound. In this article, we present two recently published in vivo studies dealing with the use of chitosan-silica hybrids for wound healing.

Hydrogels with chitosan by HMC

There are various fields of application for chitosan-based hydrogels. Hydrogels can be manufactured by chemical or physical cross-linking. The hydrophilic groups of chitosan enable the absorption of water. Chitosan hydrogels are suitable as scaffold materials for tissue engineering by mimicking the extracellular matrix. Additionally an application as drug delivery system for drugs, protein or growth factors is also possible.[1] In the following, we briefly present a number of publications about the development and application of chitosan hydrogels using chitosans by HMC.

Publications in April 2017 - Chitosan hydrogels

In April 2017, 252 articles about chitosan and chitosan derivatives were published. The International Journal of Biological Macromolecules published the highest number of chitosan-related articles (23), followed by Colloids and Surfaces B: Biointerfaces (7) and Carbohydrate Polymers (6). Researchers from China (48 articles) are as usually on the top of the list of leading countries in chitosan research. Germany can also be found among the top 10, with 5 publications in April 2017.

Publications in July 2010

In July several outstanding articles about chitosan had been published around the world.  All in all 122 articles were released in 67 different journals. With regard to the number of publications the leading countries are China (31), the USA (20) and South Korea (10).

Publications in Chitosan Research in 2008

The systematic study on chitosan and its applications also significantly gains in importance in 2008. The number of articles mentioning chitosan in their title and published in biomedical journals rise by 46% compared to the number of 2007 publications. Exploratory focus of the 692 articles were mainly in the areas biotechnology and pharmaceuticals.

Congress and fairs

Meet us in person 2024:

  • 14th PBP World Meeting/ Research Pharm, Vienna, Austria, 18.-21.03.2024
  • CPHI, Milan, Italy, 08.-10.10.2024
  • MEDICA 2024, Düsseldorf, Germany, 11.-14.11.2024

To arrange an appointment please contact Katja Richter via This email address is being protected from spambots. You need JavaScript enabled to view it.

Contact

  • Heppe Medical Chitosan GmbH
    Heinrich-Damerow-Strasse 1
    06120 Halle (Saale)
    Germany
  • Tel.: +49 (0) 345 27 996 300
    Fax: +49 (0) 345 27 996 378
  • This email address is being protected from spambots. You need JavaScript enabled to view it.
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