Chitosan HCl
- also known under the names: Chitosan hydrochloride, Chitosan chloride, Chitosani hydrochloridum
- listed in Eur. Ph., for medical applications
- Quality according to Eur. Ph.
- soluble in water
- molecular formula: H-(C8-H13-N-O5)n-H-O(C6H11-N-O4)n CL-H
Properties of Chitosan HCl
- Stronger swelling behavior than chitosan
- Water soluble
- Hemostatic effects
- Mucoadhesion
- Increases the permeability of tight junctions in the intestine
- Applications of Chitosan HCl
- Hydrogels
- Wound dressings
- Drug transport and release
We offer various Chitosan HCL specifications with different degrees of deacetylation and viscosities / molecular weights. High molecular weight chitosan chlorides are also available.
The minimum order quantity is 10g.
In the table below, you will find an overview of our offered Chitosan-HCl specifications.
| Chitoceuticals® Chitosan HCl | Article numbers | |||
| Parameter | 54040 | 54047 | 54039 | 54046 |
| Degree of Deacetylation [%] | 75-90 | >90 | 75-90 | >90 |
| Viscosity [mPas] | <20 | <20 | 20-200 | 20-200 |
| Molecular weight appr. [kDa] | <300 | <300 | 200-800 | 200-800 |
| Chloride content [%] | 10-20 | 10-20 | 10-20 | 10-20 |
| pH | 4-6 | 4-6 | 4-6 | 4-6 |
| Ash content [%] | ≤ 1 | ≤ 1 | ≤ 1 | ≤ 1 |
| Protein content [%] | ≤ 0.3 | ≤ 0.3 | ≤ 0.3 | ≤ 0.3 |
| Microbiological tests | ||||
| Total bacterial count [cfu/g] | ≤ 1000 | ≤ 1000 | ≤ 1000 | ≤ 1000 |
| Yeast and Mould | ≤ 1000 | ≤ 1000 | ≤ 1000 | ≤ 1000 |
| Heavy Metals [ppm] | ||||
| Pb | ≤ 10 | ≤ 10 | ≤ 10 | ≤ 10 |
| Hg | ≤ 1 | ≤ 1 | ≤ 1 | ≤ 1 |
Of course, we also offer our chitosan HCL specifications in Chitoceuticals® GMP compliant quality. Our GMP-compliant products are manufactured in our clean rooms according to EU GMP guidelines. As a result, they have a very low endotoxin limit as well as a very low microbial load. For our Chitosan-HCl products we also have a Drug Master File with the FDA.
Our GMP-compliant products are currently not yet available in the store and can be ordered by email. The minimum order quantity is 10g. We would be pleased to make you an offer, please
| Chitoceuticals® GMP compliant Chitosan HCl |
Article numbers | |||
| Parameter | 55040 | 55047 | 55039 | 55046 |
| Degree of Deacetylation [%] | 75-90 | >90 | 75-90 | >90 |
| Viscosity [mPa-s] | <20 | <20 | 20-200 | 20-200 |
| Molecular weight appr. [kDa] | <300 | <300 | 200-800 | 200-800 |
| Chloride content [%] | 10-20 | 10-20 | 10-20 | 10-20 |
| pH | 4-6 | 4-6 | 4-6 | 4-6 |
| Ash content [%] | ≤ 1 | ≤ 1 | ≤ 1 | ≤ 1 |
| Protein content [%] | ≤ 0.3 | ≤ 0.3 | ≤ 0.3 | ≤ 0.3 |
| Microbiological tests | ||||
| Total bacterial count [cfu/g] | ≤ 100 | ≤ 100 | ≤ 100 | ≤ 100 |
| Yeast and Mould | ≤ 100 | ≤ 100 | ≤ 100 | ≤ 100 |
| E.coli [cfu/g] | absent | absent | absent | absent |
| P.aeruginosa [cfu/g] | absent | absent | absent | absent |
| St. Aureus [cfu/g] | absent | absent | absent | absent |
| Salmonella [cfu/g] | absent | absent | absent | absent |
| Endotoxins [EU/g] | ≤ 100 | ≤ 100 | ≤ 100 | ≤ 100 |
| Heavy Metals [ppm] | ||||
| Pb | ≤ 10 | ≤ 10 | ≤ 10 | ≤ 10 |
| Hg | ≤ 1 | ≤ 1 | ≤ 1 | ≤ 1 |
Chitosan as adjuvant for vaccines
Adjuvants in vaccines are potent enhancers, which ensure that even small amounts of pathogens induce a permanent immune response. They are particularly necessary for inactivated vaccines and vaccines with antigen subunits. Several studies investigated chitosan as an adjuvant or antigen delivery system in various formulations (gels, aqueous dispersion, micro- and nanoparticles).
We have expand our chitosan chloride product range
Due to increased requests we expanded our wide product range one more time. Henceforth you can order different chitosan HCL from HMC not only in customer manufacturing, now we also provide chitosan chloride in various standard specifications with different degrees of deacetylation and viscosity-ranges. Now you can specific compare chitosan-chlorides in your research as well as generate precise properties in your pharmaceutical products.