antitumor

Chitosan-coated selenium nanoparticles for brain cancer therapy
Glioblastomas are difficult to treat due to the blood-brain barrier and drug resistance. To improve the efficacy of treating glioblastomas with selenium nanoparticles (Se-NPs), Se-NPs were coated with chitosan in the presented study.

Carboxymethyl chitosan for treatment of liver carcinomas
Hepatocellular carcinoma is a solid tumor that exhibits severe angiogenesis, cell cycle dysregulation, and evasion of apoptosis. Late diagnosis in a large proportion of patients is making the carcinomas inoperable, and various chemotherapeutic agents are used. Due to the numerous side effects of known chemotherapeutic agents, intensive research is performed on the use of natural products and their synthetic analogues. The authors of the presented study investigated the effect of carboxymethyl chitosan oligosaccharides on the growth of hepatocellular tumors in mice.

Publications in June 2011
70 articles were published in June, an obvious decrease of publications. For comparison, 84 articles were published in May. In June 2010 with 129 articles almost twice as much articles appeared, compared to this June.