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GMP Chitosan, medical device chitosan, pure chitin, pharma chitosan, chitosan derivatives, GMP, Quality, producer | Heppe Medical Chitosan

Microfluidics for the production of chitosan-TPP nanoparticles

Microfluidics can precisely control the physiochemical properties of nanoparticles by mixing to the nanoliter. For this reason, nanoparticles for the transport of peptide drugs are to be developed in the study presented here with the help of chitosan from Heppe Medical Chitosan GmbH.

Microfluidics as a platform technology for the production of chitosan nanoparticles

The preparation of chitosan-based nanoparticles by ionotrophic gelation often leads to high batch-to-batch variability as well as in low reproducibility. A possible solution to this could be controlled mixing on a microfluidic scale. In the study presented here, chitosan tripolyphosphate nanoparticles with siRNA, mRNA and β-galactosidase as cargo will be prepared using microfluidics.

Chitosan in microfluidic systems

In microfluidic systems, analyses can be performed on a miniaturized scale without the use of complex laboratory equipment. In this context, DNA purification and concentration pose a particular challenge. To improve this, a disposable microfluidic device is functionalized with different chitosans for DNA binding in the presented study. This will then be used to detect eDNA of invasive species from river water samples.

Congress and fairs

Meet us in person 2024:

  • 14th PBP World Meeting/ Research Pharm, Vienna, Austria, 18.-21.03.2024
  • EPNOE Workshop on Analytics of Polysaccharides, ETH Zürich, Zürich, Switzerland, 25.-26.06.2024
  • CPHI, Milan, Italy, 08.-10.10.2024
  • MEDICA 2024, Düsseldorf, Germany, 11.-14.11.2024

To arrange an appointment please contact Katja Richter via This email address is being protected from spambots. You need JavaScript enabled to view it.


  • Heppe Medical Chitosan GmbH
    Heinrich-Damerow-Strasse 1
    06120 Halle (Saale)
  • Tel.: +49 (0) 345 27 996 300
    Fax: +49 (0) 345 27 996 378
  • This email address is being protected from spambots. You need JavaScript enabled to view it.

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