Artificially produced nerve conduits are promising alternatives to autologous nerve grafts in the treatment of damaged nerves. In this study, the physiochemical properties of chitosan/poly-ε-caprolactone nerve conduits will be improved by using the chitosan crosslinker genipin.
Chitosan bioglass networks can be used as biomaterials in medicine, for example, as bone implants. Their physiochemical and mechanical properties can be improved by crosslinkers and various stabilization methods. In the presented study, six of them were compared with each other.
Hydrogels can have versatile applications in biomedicine by forming a 3D network. In the study presented here, an antibacterial, adhesive, self-repairing hydrogel was prepared from carboxymethylchitosan (CMC) and oligomeric polycyanidin (OPC) and the influence of OPC content was investigated.
The healing process of a wound injury follows the steps of hemostasis, inflammation, cell proliferation, and regeneration until complete healing of the damaged tissue. In chronic wounds, the progress of these steps is disturbed, leaving the wounds inflamed for a long time. In an aging society with bad health habits (poor diet, little exercise), the number of chronic wounds is going to increase. Therefore, the research on materials that improve wound healing is important. The publications presented below are devoted to research about chitosan-based materials for the treatment of chronic wounds.
In September and October, 276 chitosan-related articles have been released. The main topics addressed chitosan in evaluation studies, pharmaceutical preparations, nanoparticles and tissue engineering. The highest number of publications was performed by the leading nations China (73 articles), USA (28) and India (22). German scientists published 8 articles, placing them in the top-ten list.
In the mid-year, 227 articles have been released about chitosan. The main topics addressed nanoparticles, pharmaceutical preparations, evaluation studies, animals and humans. The leading nations in publishing chitosan-related articles are again China (69 articles), USA (28) and India (21). German scientists published 5 reports.
The number of publications increased in October. So 144 articles about chitosan were released. Looking at the amount of publications the same countries as in September led the list.
Most publications came from China. In October 40 articles were published there. With 13 published articles India was in second place, followed by the USA with overall 11 publications.
In April the rate of publications with chitosan slightly dropped. 90 articles were published which means 7 less than in April 2010. In comparison to March 2011 38 fewer papers presented results in chitosan research.
