Publications in 2015 - a summary

The development of the chitosan research and chitosan application is steadily proceeding. More than 2100 reports about chitosan and chitosan derivatives were published in 2015. The highest number of publications was performed by the leading nations China (589), India (250), the United States (214) and the European area as a whole.

In the year 2015 the number of chitosan-related articles has increased. For instance in 2013 were published around 1800 reports, in 2014 around 1900 and in 2015 more than 2100 reports about Chitosan. The overview shows the Top 10 lists of the publications.

Top Countries	Publications		Top Journals	Publications
China	589		Int J Biol Macromol	183
India	250		Carbohydr Polym	169
United States	214		Acs Appl Mater Interfaces	59
Iran	96		Mater Sci Eng C Mater Biol Appl	58
South Korea	87		Colloids Surf B Biointerfaces	57
Brazil	81		Int J Pharm	53
Taiwan	75		Biomaterials	36
Italy	72		Int J Nanomedicine	34
Spain	69		Acta Biomater	32
Portugal	68		J Biomed Mater Res A	31

Table: Top-Countries, Top-Journals, with the most chitosan articles in 2015
Source: GoPubMed

As in previous years, numerous chitosan-related articles were published by these Top authors. Chitosan is increasingly establishing itself in the field of pharmacy and medical technology. That reveal the topics of publications of previous years until now.

Top Authors	Publications		Top Terms	Publications
Tang, C.	589		Chitosan	1934
Gallucci, M.	250		Evaluation Studies as Topic	636
Reis, R.	214		Nanoparticles	623
Bernkop-Schnürch, A.	96		Pharmaceutical Preparations	548
Kumar, P.	87		Tissues	382

Tabelle: Top-Journale, Top-Themen, in denen die meisten Chitosan-bezogenen Artikel veröffentlicht wurden; im Jahr 2015
Quelle: GoPubMed

There were many trendsetting reports from the chitosan research in 2015. In addition to 90 reviews there were two clinical trials about Chitosan (pubmed). For you we have prepared a selection of interesting reviews and clinical trials of the last year. These articles are free and completely accessible.

Please note also our monthly reports of the year 2015.

Chitosan and Its Potential Use as a Scaffold for Tissue Engineering in Regenerative Medicine

Martin Rodríguez-Vázquez, Brenda Vega-Ruiz, Rodrigo Ramos-Zúñiga, Daniel Alexander Saldaña-Koppel, and Luis Fernando Quiñones-Olvera

This review about tissue engineering gives an overview about the effects of the Chitosan-specification on the properties of the resulting scaffolds. The summary of the physicochemical properties includes following points:

• pH Dependence and Solubility
• Degree of Deacetylation (DD)
• Molecular Weight
• Porosity
• Water Absorption Capacity
• Mechanical Properties

Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609393/

Based hydrogels: characteristics and pharmaceutical applications

F. Ahmadi, Z. Oveisi, S. Mohammadi Samani, Z. Amoozgar

Chitosan as an ingredient into hydrogels has the ability to transport pharmaceutical ingredients. It can be utilized for targeted drug delivery. The following standard methods will be explained in the article:

• Cross-linking via cross-linkers
• Cross-linking via photopolymerization
• Ionically cross-linked chitosan hydrogel
• Polyelectrolyte complexed chitosan hydrogel

Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578208/

Chitosan: An Update on Potential Biomedical and Pharmaceutical Applications

Randy Chi Fai Cheung, Tzi Bun Ng, Jack Ho Wong, and Wai Yee Chan
Paola Laurienzo, Academic Editor

Chitosan, as an ingredient into pharmaceuticals, attracts more and more the interest of experts and scientists into the field of pharmacy and biomedicine. The report of “Marine Drugs” summarizes the current knowledge about chitosan. Here you can find a detailed overview about the chitosan-bioactivity.

Following points are included:

• Antibacterial Activity
• Antifungal Activity
• Anti-HIV-1 Activity and for Construction of Nanoparticles Loaded with Anti-HIV Drugs
• Antitumor Activity
• Antioxidant Activity

Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557018/