Current clinical studies with chitosan
Clinical studies serve evidence-based medicine and enable the development and application of new, innovative medical products and drugs. At the moment, there are several clinical studies with chitosan-containing products or devices, for example, in relation to wound healing, tumor detection or Covid-19. In this article, we would like to give you an overview of the ongoing studies.
Tags: chitosan, Clinical Studies Chitosan
Currently, 20 clinical trials related to chitosan with the status 'recruiting' and 'not yet recruiting' can be found on https://www.clinicaltrials.gov/ (as of June 14, 2022). This is twice as many compared to 2020 and 2018.
The table below provides an overview of ongoing studies in terms of title, disease, medical intervention/device, status, and study location.
|
Title
|
Condition
|
Intervention
|
Status
|
Location
|
|
|
1 |
Efficacy and Safety of Sericin and Chitosan Cream for Preventing and Limiting the Progressive of Pressure Sore
|
Pressure Ulcer
|
Other: sericin and chitosan cream
|
Recruiting
|
Bangkok, Thailand
|
|
2 |
Long-term Safety and Performance of KiOmedine CM-Chitosan Supplementation in Advanced Symptomatic Knee Osteoarthritis
|
Osteoarthritis, Knee
|
Device: KiOmedine® CM-Chitosan
Device: Synvisc-One®
|
Recruiting
|
Ghent, Belgium
|
|
3 |
The Effectiveness of Antibacterial Therapeutic Clothing Based on Silver or Chitosan as Compared with Non-antibacterial Therapeutic Clothing in Patients with Moderate to Severe Atopic Dermatitis
|
Atopic Dermatitis
|
Device: DermaCura® Chitosan based antimicrobial therapeutic clothing
Device: Binamed® silver based antimicrobial therapeutic clothing
Device: Binamed® therapeutic clothing without antimicrobial agents
|
Recruiting
|
Rotterdam, Netherlands
|
|
4 |
MicroFIBERgut: Effects of Lifestyle Changes and Chitosan on Gut Microbiota and Weight Management
|
Obesity
Lifestyle
|
Behavioral: Lifestyle changes
Dietary Supplement: Chitosan
Other: Placebo
|
Recruiting
|
Mosfellsbaer, Iceland
|
|
5 |
Effectiveness of a Novel Respirator with Chitosan Nanoparticles
|
Covid19
SARS-CoV Infection
Worker-Patient Transmission, Healthcare
|
Device: VESTA respirator
Device: Conventional N95 respirator
|
Recruiting
|
Brasília, Brazil
|
|
6 |
Metabolic Effect of an Innovative Chitosan Formulation
|
Hypercholesterolemia
Overweight and Obesity
|
Device: Medical Device (Kaptufat®)
Other: Placebo
|
Not yet recruiting
|
Bologna, Italy
|
|
7 |
Evaluation of the Cell Detachment Ratio on pH-responsive Chitosan as a Prognostic Factor in Lung Cancer
|
Clinical Decision-Making
Early Detection of Cancer
|
|
Recruiting
|
Taipei, Taiwan
|
|
8 |
Develop the First Aid Medical Supplies for Hemostasis and Bacteriostasis With Clinical Trial
|
Cesarean Section
|
Device: Regular Gauze
Device: Chitosan Dressing
|
Recruiting
|
Taipei, Taiwan
|
|
9 |
Clinical & Radiographic Evaluation of LSTR in Non-vital Primary Molars Using Two Different Vehicles
|
Resorption of Tooth or Root
|
Drug: Double antibiotic paste mixed with chitosan nanoparticles
Drug: Double antibiotic paste mixed with propylene glycol
|
Not yet recruiting
|
|
|
10 |
SPiT-frequency; the Effect of Increased Frequency of Intervention on Post-surgical Peri-implant Inflammation
|
Peri-Implantitis
|
Other: Submucosal supportive therapy
|
Not yet recruiting
|
|
|
11 |
To Evaluate the Efficacy and Safety of MaxioCel Versus Aquacel Extra for the Management of Chronic Wounds
|
Wound
|
Device: MaxioCel
Device: AquaCel Extra
|
Not yet recruiting
|
Hyderabad, India
Vijayawada, India
|
|
12 |
NOVAPAK Nasal Packing in Shellfish Allergic Patients
|
Shellfish Hypersensitivity
Epistaxis
|
Device: NOVAPAK nasal packing applied to forearm
Device: NOVAPAK nasal packing applied to nasal cavity
|
Not yet recruiting
|
London, Ontario, Canada
|
|
13 |
Combination of InnoSEAL Plus TR Band Compared to TR Band Alone
|
Radial Artery Occlusion
Hematoma
|
Device: InnoSEAL+TRB
Device: TRB alone
|
Recruiting
|
Karachi, Sind, Pakistan
|
|
14 |
A Comparison of JointRep® and Microfracture in Repair of Cartilage Lesions on the Femoral Condyle or Trochlea
|
Chondral Defect
Articular Cartilage Defect
Articular Cartilage Disorder of Knee
|
Device: JointRep®
Procedure: Microfracture
|
Recruiting
|
Kogarah, New South Wales, Australia
Newcastle, New South Wales,
Randwick, New South Wales, Australia
(and 3 more)
|
|
15 |
Intratumoral Injection of IP-001 Following Thermal Ablation in Patients With Advanced Solid Tumors
|
Advanced Solid Tumors
|
Drug: IP-001 Device: Thermal Ablation
|
Recruiting
|
Chur, Switzerland
Lausanne, Switzerland
St. Gallen, Switzerland
|
|
16 |
Efficacy of BST-CarGel in Treating Chondral Lesions of the Hip
|
Disorder of Hip Region
|
Device: BST-CarGel Procedure: Microfracture
|
Not yet recruiting
|
|
|
17 |
Ortho-R® for Rotator Cuff Repair Compared With Standard of Care Rotator Cuff Repair Without Ortho-R®
|
Rotator Cuff Tears
|
Drug: Ortho-R/PRP
|
Not yet recruiting
|
|
|
18 |
Superficial Partial-Thickness Burn Study
|
Superficial Partial Thickness Burn
|
Device: Catasyn™ Advanced Technology Hydrogel and SynePure™ Wound Cleanser
Drug: Silver Sulfadiazine
|
Recruiting
|
Pittsburgh, Pennsylvania, United States
|
|
19 |
Radial Artery Puncture Hemostasis Study
|
Radial Artery Hemostasis
|
Device: Radial artery hemostasis
|
Recruiting
|
Szeged, Csongád-Csanád, Hungary
Debrecen, Hajdú-Bihar, Hungary
Budapest, Hungary
|
|
20 |
P11-4 and Nanosilver Fluoride Varnish in Treatment of White Spot Carious Lesions
|
White Spot Lesion
|
Other: self-assembling peptide
Other: nanosilver fluoride varnish
Other: sodium fluoride varnish
|
Recruiting
|
Alexandria, Egypt
|