layer-by-layer

Chronic wounds represent a major burden on the quality of life of those affected. To improve their situation, multilayer films of chitosan, alginate and the fibroblast growth factor FGF2 were prepared in the presented study and their potential as wound dressings was investigated.

The healing process of a wound injury follows the steps of hemostasis, inflammation, cell proliferation, and regeneration until complete healing of the damaged tissue. In chronic wounds, the progress of these steps is disturbed, leaving the wounds inflamed for a long time. In an aging society with bad health habits (poor diet, little exercise), the number of chronic wounds is going to increase. Therefore, the research on materials that improve wound healing is important. The publications presented below are devoted to research about chitosan-based materials for the treatment of chronic wounds.

343 articles about chitosan were published in February 2017. Main topics address chitosan in connection to nanoparticles, tissues and in evaluation studies. Top countries in chitosan research were China (57), India (29) and USA (21).

The year 2017 started in January with a high number of new publications about chitosan and chitosan derivatives (383 articles). Top countries in publishing about chitosan were China (75), the United States (39) and India (25). This time we focus on the layer-by-layer (LbL) assembly of chitosan mostly together with other biomaterials and possible applications.

The team of Prof. Maryam Tabrizian from McGill University in Montreal, Canada developed a procedure that might be the basis for the application of donated blood independently from the blood group.